Publications 2016

Partner 2

 

Bedioune, I., P. Bobin, S. Karam, M. Lindner, D. Mika, P. Lechene, J. Leroy, R. Fischmeister and G. Vandecasteele (2016). "[Cyclic nucleotide phosphodiesterases: role in the heart and therapeutic perspectives]." Biol Aujourdhui 210(3): 127-138.

 

Ben Salem, I., A. Prola, M. Boussabbeh, A. Guilbert, H. Bacha, C. Lemaire and S. Abid-Essefi (2016). "Activation of ER stress and apoptosis by α- and β-zearalenol in HCT116 cells, protective role of Quercetin." NeuroToxicology 53: 334-342.

 

Bobin, P., A. Varin, F. Lefebvre, R. Fischmeister, G. Vandecasteele and J. Leroy (2016). "Calmodulin kinase II inhibition limits the pro-arrhythmic Ca<sup>2+</sup> waves induced by cAMP-phosphodiesterase inhibitors." Cardiovascular Research.

 

Calderón-Sánchez, E. M., A. Domínguez-Rodríguez, J. López-Haldón, M. F. Jiménez-Navarro, A. M. Gómez, T. Smani and A. Ordóñez (2016). "Cardioprotective Effect of Ranolazine in the Process of Ischemia-reperfusion in Adult Rat Cardiomyocytes." Revista Española de Cardiología (English Edition) 69(1): 45-53.

 

Cousin, F. J., S. Jouan-Lanhouet, N. Théret, C. Brenner, E. Jouan, G. Le Moigne-Muller, M.-T. Dimanche-Boitrel and G. Jan (2016). "The probiotic Propionibacterium freudenreichii as a new adjuvant for TRAIL-based therapy in colorectal cancer." Oncotarget.

 

Pedroso, D., A. R. Nunes, L. N. Diogo, C. Oudot, E. C. Monteiro, C. Brenner and H. L. A. Vieira (2016). "Hippocampal neurogenesis response: What can we expect from two different models of hypertension?" Brain Research 1646: 199-206.

 

Torrente AG, Mesirca P, Neco P, Rizzetto R, Dubel S, Barrere C, Sinegger-Brauns M, Striessnig J, Richard S, Nargeot J, Gomez AM, Mangoni ME. L-type Cav1.3 Channels Regulate Ryanodine Receptor-dependent Ca2+ Release during Sino-Atrial Node Pacemaker Activity. Cardiovasc Res. 109(3):451-61, 2016.

 

Vettel, C., M. Lindner, M. Dewenter, K. Lorenz, C. Schanbacher, M. Riedel, S. Lämmle, S. Meinecke, F. E. Mason, S. Sossalla, A. Geerts, M. Hoffmann, F. Wunder, F. J. Brunner, T. Wieland, H. Mehel, S. Karam, P. Lechêne, J. Leroy, G. Vandecasteele, M. Wagner, R. Fischmeister and A. El-Armouche (2016). "Phosphodiesterase 2 Protects Against Catecholamine-Induced Arrhythmia and Preserves Contractile Function After Myocardial Infarction." Circulation Research.

 

Partner 3

 

Biajoux, V., J. Natt, C. Freitas, N. Alouche, A. Sacquin, P. Hemon, F. Gaudin, N. Fazilleau, M. Espéli and K. Balabanian (2016). "Efficient Plasma Cell Differentiation and Trafficking Require Cxcr4 Desensitization." Cell Reports 17(1): 193-205.

 

Calmette, J., M. Bertrand, M. Vétillard, M. Ellouze, S. Flint, V. Nicolas, A. Biola-Vidamment, M. Pallardy, E. Morand, F. Bachelerie, V. Godot and G. Schlecht-Louf (2016). "Glucocorticoid-Induced Leucine Zipper Protein Controls Macropinocytosis in Dendritic Cells." The Journal of Immunology 197(11): 4247-4256.

 

Espéli, M., K. G. C. Smith and M. R. Clatworthy (2016). "FcγRIIB and autoimmunity." Immunological Reviews 269(1): 194-211.

 

Ferrere, G., A. Leroux, L. Wrzosek, V. Puchois, F. Gaudin, D. Ciocan, M.-L. Renoud, S. Naveau, G. Perlemuter and A.-M. Cassard (2016). "Activation of Kupffer Cells Is Associated with a Specific Dysbiosis Induced by Fructose or High Fat Diet in Mice." PLoS ONE 11(1): e0146177.

 

Maciejewski-Duval, A., F. Meuris, A. Bignon, M. L. Aknin, K. Balabanian, L. Faivre, M. Pasquet, V. Barlogis, C. Fieschi, C. Bellanne-Chantelot, J. Donadieu, G. Schlecht-Louf, V. Marin-Esteban and F. Bachelerie (2016). "Altered chemotactic response to CXCL12 in patients carrying GATA2 mutations." Journal of Leukocyte Biology 99(6): 1065-1076.

 

Meuris, F., F. Gaudin, M. L. Aknin, P. Hemon, D. Berrebi and F. Bachelerie (2016). "Symptomatic Improvement in Human Papillomavirus-Induced Epithelial Neoplasia by Specific Targeting of the CXCR4 Chemokine Receptor." Journal of Investigative Dermatology 136(2): 473-480.

 

Pionnier, N., E. Brotin, G. Karadjian, P. Hemon, F. Gaudin-Nome, N. Vallarino-Lhermitte, A. Nieguitsila, F. Fercoq, M. L. Aknin, V. Marin-Esteban, S. Chollet-Martin, G. Schlecht-Louf, F. Bachelerie and C. Martin (2016). "Neutropenic Mice Provide Insight into the Role of Skin-Infiltrating Neutrophils in the Host Protective Immunity against Filarial Infective Larvae." Plos Neglected Tropical Diseases 10(4): 24.

 

Robert, O., H. Boujedidi, A. Bigorgne, G. Ferrere, C. S. Voican, S. Vettorazzi, J. P. Tuckermann, L. Bouchet-Delbos, T. Tran, P. Hemon, V. Puchois, I. Dagher, R. Douard, F. Gaudin, H. Gary-Gouy, F. Capel, I. Durand-Gasselin, S. Prévot, S. Rousset, S. Naveau, V. Godot, D. Emilie, M. Lombès, G. Perlemuter and A.-M. Cassard (2016). "Decreased expression of the glucocorticoid receptor-GILZ pathway in Kupffer cells promotes liver inflammation in obese mice." Journal of Hepatology 64(4): 916-924.

 

Partner 6

 

Dierick, F., T. Hery, B. Hoareau-Coudert, N. Mougenot, V. Monceau, C. Claude, M. Crisan, V. Besson, P. Dorfmuller, G. Marodon, E. Fadel, M. Humbert, E. Yaniz-Galende, J. S. Hulot, G. Marazzi, D. Sassoon, F. Soubrier and S. Nadaud (2016). "Resident PW1(+) Progenitor Cells Participate in Vascular Remodeling During Pulmonary Arterial Hypertension." Circulation Research 118(5): 822-833.

 

Guignabert, C., C. Phan, A. Seferian, A. Huertas, L. Tu, R. Thuillet, C. Sattler, M. Le Hiress, Y. Tamura, E.-M. Jutant, M.-C. Chaumais, S. Bouchet, B. Manéglier, M. Molimard, P. Rousselot, O. Sitbon, G. Simonneau, D. Montani and M. Humbert (2016). "Dasatinib induces lung vascular toxicity and predisposes to pulmonary hypertension." The Journal of Clinical Investigation 126(9): 3207-3218.

 

Günther, S. and F. Perros (2016). "Utilisation d’un modèle expérimental de maladie veino-occlusive pulmonaire." Revue des Maladies Respiratoires 33, Supplement: A289-A290.

 

Huertas, A., C. Phan, J. Bordenave, L. Tu, R. Thuillet, M. Le Hiress, J. Avouac, Y. Tamura, Y. Allanore, R. Jovan, O. Sitbon, C. Guignabert and M. Humbert (2016). "Regulatory T Cell Dysfunction in Idiopathic, Heritable and Connective Tissue-Associated Pulmonary Arterial Hypertension." Chest 149(6): 1482-1493.

 

Lador.F, A. Bringard, S. Bengueddache, G. Ferretti, K. Bendjelid, P. M. Soccal, S. Noble, M. Beghetti, D. Chemla, Hervé. P. and O. Sitbon (2016). "Kinetics of Cardiac Output at the Onset of Exercise in Precapillary Pulmonary Hypertension." BioMed Research International 2016: 8.

 

Lau, E., L. Godinas, D. Montani, L. Savale, O. Sitbon, M. Humbert, D. Chemla and P. Herve (2016). "DIAGNOSTIC ACCURACY AND CONCORDANCE OF DIFFERENT CRITERIA FOR EXERCISE PULMONARY HYPERTENSION." Respirology 21: 89-89.

 

Lau, E. M. T., D. Chemla, L. Godinas, K. X. Zhu, O. Sitbon, L. Savale, D. Montani, X. Jais, D. S. Celermajer, G. Simonneau, M. Humbert and P. Herve (2016). "Loss of Vascular Distensibility During Exercise Is an Early Hemodynamic Marker of Pulmonary Vascular Disease." Chest 149(2): 353-361.

 

Lau, E. M. T., L. Godinas, O. Sitbon, D. Montani, L. Savale, X. Jaïs, F. Lador, S. Gunther, D. S. Celermajer, G. Simonneau, M. Humbert, D. Chemla and P. Herve (2016). "Resting pulmonary artery pressure of 21–24 mmHg predicts abnormal exercise haemodynamics." European Respiratory Journal 47(5): 1436-1444.

 

O'Connell, C., D. Amar, A. Boucly, L. Savale, X. Jais, M. C. Chaumais, D. Montani, M. Humbert, G. Simonneau and O. Sitbon (2016). "Comparative Safety and Tolerability of Prostacyclins in Pulmonary Hypertension." Drug Safety 39(4): 287-294.

 

Regent, A., K. H. Ly, S. Lofek, G. Clary, M. Tamby, N. Tamas, C. Federici, C. Broussard, P. Chafey, E. Liaudet-Coopman, M. Humbert, F. Perros and L. Mouthon (2016). "Proteomic analysis of vascular smooth muscle cells in physiological condition and in pulmonary arterial hypertension: Toward contractile versus synthetic phenotypes." Proteomics 16(20): 2637-2649.

 

Reviron-Rabec, L., B. Girerd, A. Seferian, K. Campbell, S. Brosseau, E. Bergot, M. Humbert, G. Zalcman and D. Montani (2016). "Pulmonary complications of type 1 neurofibromatosis." Revue des Maladies Respiratoires 33(6): 460-473.

 

Sanges, S., D. Launay, R. L. Rhee, O. Sitbon, E. Hachulla, L. Mouthon, L. Guillevin, L. Rottat, D. Montani, P. De Groote, V. Cottin, P. Magro, G. Prevot, F. Bauer, E. Bergot, C. Chabanne, M. Reynaud-Gaubert, S. Leroy, M. Canuet, O. Sanchez, C. Gut-Gobert, C. Dauphin, C. Pison, C. Boissin, G. Habib, P. Clerson, F. Conesa, J. F. Cordier, S. M. Kawut, G. Simonneau and M. Humbert (2016). "A prospective study of the 6 min walk test as a surrogate marker for haemodynamics in two independent cohorts of treatment-naive systemic sclerosis-associated pulmonary arterial hypertension." Annals of the Rheumatic Diseases 75(8): 1457-1465.

 

Sanges, S., C. Yelnik, O. Sitbon, O. Benveniste, K. Mariampillai, M. Philips-Houlbracq, C. Pison, C. Deligny, P. Y. Hatron, L. Rottat, M. Humbert and E. Hachulla (2016). "Hypertension artérielle pulmonaire au cours des myopathies inflammatoires idiopathiques : données du Registre national de l’hypertension pulmonaire et revue de la littérature." La Revue de Médecine Interne 37, Supplement 1: A96-A97.

 

Sanges, S., C. M. Yelnik, O. Sitbon, O. Benveniste, K. Mariampillai, M. Phillips-Houlbracq, C. Pison, C. Deligny, J. Inamo, V. Cottin, L. Mouthon, D. Launay, M. Lambert, P. Y. Hatron, L. Rottat, M. Humbert and E. Hachulla (2016). "Pulmonary arterial hypertension in idiopathic inflammatory myopathies: Data from the French pulmonary hypertension registry and review of the literature." Medicine 95(39): 11.

 

Szulcek, R., C. M. Happé, N. Rol, R. D. Fontijn, C. Dickhoff, K. J. Hartemink, K. Grünberg, L. Tu, W. Timens, G. D. Nossent, M. A. Paul, T. A. Leyen, A. J. Horrevoets, F. S. d. Man, C. Guignabert, P. B. Yu, A. Vonk-Noordegraaf, G. P. v. N. Amerongen and H. J. Bogaard (2016). "Delayed Microvascular Shear Adaptation in Pulmonary Arterial Hypertension. Role of Platelet Endothelial Cell Adhesion Molecule-1 Cleavage." American Journal of Respiratory and Critical Care Medicine 193(12): 1410-1420.

 

Tu, L., M.-R. Ghigna, C. Phan, J. Bordenave, M. Le Hiress, R. Thuillet, N. Ricard, A. Huertas, M. Humbert and C. Guignabert (2016). "Vers de nouvelles cibles pour le traitement de l’hypertension artérielle pulmonaire : Importance des communications cellulaires." Biologie Aujourd'hui 210(2): 65-78.

 

Van der Bruggen, C. E., C. M. Happe, P. Dorfmuller, P. Trip, O. A. Spruijt, N. Rol, F. P. Hoevenaars, A. C. Houweling, B. Girerd, J. T. Marcus, O. Mercier, M. Humbert, M. L. Handoko, J. van der Velden, A. V. Noordegraaf, H. J. Bogaard, M. J. Goumans and F. S. de Man (2016). "Bone Morphogenetic Protein Receptor Type 2 Mutation in Pulmonary Arterial Hypertension A View on the Right Ventricle." Circulation 133(18): 1747.

 

Partner 7

 

Bogaerts, P., G. Cuzon, S. Evrard, M. Hoebeke, T. Naas and Y. Glupczynski (2016). "Evaluation of a DNA microarray for rapid detection of the most prevalent extended-spectrum beta-lactamases, plasmid-mediated cephalosporinases and carbapenemases in Enterobacteriaceae, Pseudomonas and Acinetobacter." International Journal of Antimicrobial Agents 48(2): 189-193.

 

Chihi, H., R. A. Bonnin, A. Bourouis, S. Mahrouki, S. Besbes, M. B. Moussa, O. Belhadj and T. Naas (2016). "GES-11-producing Acinetobacter baumannii clinical isolates from Tunisian hospitals: Long-term dissemination of GES-type carbapenemases in North Africa." Journal of Global Antimicrobial Resistance 5: 47-50.

 

Cuzon, G., P. Bogaerts, C. Bauraing, T. D. Huang, R. A. Bonnin, Y. Glupczynski and T. Naas (2016). "Spread of Plasmids Carrying Multiple GES Variants." Antimicrobial Agents and Chemotherapy 60(8): 5040-5043.

 

Cuzon, G., M. Levy, E. Jacob, L. Dortet and T. Naas (2016). "IMI-1-producing Enterobacter cloacae clinical isolate from Tahiti, French Polynesia." Journal of Global Antimicrobial Resistance 5: 1-2.

 

Dortet, L., R. Bonnin, A. Jousset, L. Gauthier and T. Naas (2016). "Émergence de la résistance à la colistine chez les entérobactéries : une brèche dans le dernier rempart contre la pan-résistance !" Journal des Anti-infectieux 18(4): 139-159.

 

Dortet, L., R. A. Bonnin, S. Bernabeu, L. Escaut, D. Vittecoq, D. Girlich, D. Imanci, N. Fortineau and T. Naas (2016). "First Occurrence of OXA-72-Producing Acinetobacter baumannii in Serbia." Antimicrobial Agents and Chemotherapy 60(10): 5724-5730.

 

Dortet, L., G. Cuzon, P. Plesiat and T. Naas (2016). "Prospective evaluation of an algorithm for the phenotypic screening of carbapenemase-producing Enterobacteriaceae." Journal of Antimicrobial Chemotherapy 71(1): 135-140.

 

Dortet, L., M. Fusaro and T. Naas (2016). "Improvement of the Xpert Carba-R Kit for the Detection of Carbapenemase-Producing Enterobacteriaceae." Antimicrobial Agents and Chemotherapy 60(6): 3832-3837.

 

Dortet, L., A. Jousset, V. Sainte-Rose, G. Cuzon and T. Naas (2016). "Prospective evaluation of the OXA-48 K-SeT assay, an immunochromatographic test for the rapid detection of OXA-48-type carbapenemases." Journal of Antimicrobial Chemotherapy 71(7): 1834-1840.

 

Naas, T., G. Cuzon, A. L. Robinson, Z. Andrianirina, P. Imbert, E. Ratsima, Z. N. Ranosiarisoa, P. Nordmann and J. Raymond (2016). "Neonatal infections with multidrug-resistant ESBL-producing E. cloacae and K. pneumoniae in Neonatal Units of two different Hospitals in Antananarivo, Madagascar." Bmc Infectious Diseases 16: 10.

 

Partner 8

 

Deutsch, E., C. Haie-Meder, M. A. Bayar, M. Mondini, M. Laporte, R. Mazeron, J. Adam, A. Varga, G. Vassal, N. Magne, C. Chargari, E. Lanoy, P. Pautier, A. Levy and J. C. Soria (2016). "Phase I trial evaluating the antiviral agent Cidofovir in combination with chemoradiation in cervical cancer patients." Oncotarget 7(18): 25549-25557.

 

Partner 9

 

Pailler, E., M. Oulhen, F. Billiot, A. Galland, N. Auger, V. Faugeroux, C. Laplace-Builhe, B. Besse, Y. Loriot, M. Ngo-Camus, M. Hemanda, C. R. Lindsay, J. C. Soria, P. Vielh and F. Farace (2016). "Method for semi-automated microscopy of filtration-enriched circulating tumor cells." Bmc Cancer 16: 15.

 

Partner 10

 

Thebault, S., M. Agez, X. K. Chi, J. Stojko, V. Cura, S. B. Telerman, L. Maillet, F. Gautier, I. Billas-Massobrio, C. Birck, N. Troffer-Charlier, T. Karafin, J. Honore, A. Senff-Ribeiro, S. Montessuit, C. M. Johnson, P. Juin, S. Cianferani, J. C. Martinou, D. W. Andrews, R. Amson, A. Telerman and J. Cavarelli (2016). "TCTP contains a BH3-like domain, which instead of inhibiting, activates Bcl-xL." Scientific Reports 6: 11.

 

Partner 11

Araye, A., A. Goudet, J. Barbier, S. Pichard, B. Baron, P. England, J. Perez, S. Zinn-Justin, A. Chenal and D. Gillet (2016). "The Translocation Domain of Botulinum Neurotoxin A Moderates the Propensity of the Catalytic Domain to Interact with Membranes at Acidic pH." Plos One 11(4): 20.

Babon, A., T. Wurceldorf, C. Almunia, S. Pichard, A. Chenal, C. Buhot, B. Beaumelle and D. Gillet (2016). "Bee venom phospholipase A(2) as a membrane-binding vector for cell surface display or internalization of soluble proteins." Toxicon 116: 56-62.

Boelen, L., P. K. O'Neill, K. J. Quigley, C. J. Reynolds, B. Maillere, J. H. Robinson, G. Lertmemongkolchai, D. M. Altmann, R. J. Boyton and B. Asquith (2016). "BIITE: A Tool to Determine HLA Class II Epitopes from T Cell ELISpot Data." Plos Computational Biology 12(3): 18.

Bordenave, T., M. Helle, F. Beau, D. Georgiadis, L. Tepshi, M. Bernes, Y. P. Ye, L. Levenez, E. Poquet, H. Nozach, M. Razavian, J. Toczek, E. A. Stura, V. Dive, M. M. SadeghiP and L. Devel (2016). "Synthesis and in Vitro and in Vivo Evaluation of MMP-12 Selective Optical Probes." Bioconjugate Chemistry 27(10): 2407-2417.

Jacquot, G., P. Lécorché, J.-D. Malcor, M. Laurencin, M. Smirnova, K. Varini, C. Malicet, F. Gassiot, K. Abouzid, A. Faucon, M. David, N. Gaudin, M. Masse, G. Ferracci, V. Dive, S. Cisternino and M. Khrestchatisky (2016). "Optimization and in Vivo Validation of Peptide Vectors Targeting the LDL Receptor." Molecular Pharmaceutics 13(12): 4094-4105.

Michel, G., B. Ferrua, P. Munro, L. Boyer, N. Mathal, D. Gillet, P. Marty and E. Lemichez (2016). "Immunoadjuvant Properties of the Rho Activating Factor CNF1 in Prophylactic and Curative Vaccination against Leishmania infantum." Plos One 11(6): 13.

Scornet, N., S. Delarue-Cochin, M. E. Azoury, M. Le Mignon, J. A. Chemelle, E. Nony, B. Maillere, R. Terreux, M. Pallardy and D. Joseph (2016). "Bioinspired Design and Oriented Synthesis of Immunogenic Site-Specifically Penicilloylated Peptides." Bioconjugate Chemistry 27(11): 2629-2645.

Partner 12

Donck, S., J. Fize, E. Gravel, E. Doris and V. Artero (2016). "Supramolecular assembly of cobaloxime on nanoring-coated carbon nanotubes: addressing the stability of the pyridine-cobalt linkage under hydrogen evolution turnover conditions." Chemical Communications 52(79): 11783-11786.

Foillard, S., J. Russier, C. Seifert, H. Dumortier and E. Doris (2016). "Carbon nanotube-mediated delivery of budesonide to macrophages." Rsc Advances 6(58): 53282-53287.

Nguyen, D.-V., P. Prakash, E. Gravel and E. Doris (2016). "Triphenylbismuth carbonate-mediated oxidation of hydroxylamines to nitrones and in situ 1,3-dipolar cycloaddition." RSC Advances 6(92): 89238-89241.

Prakash, P., E. Gravel, H. Y. Li, F. Miserque, A. Habert, M. den Hertog, W. L. Ling, I. N. N. Namboothiri and E. Doris (2016). "Direct and co-catalytic oxidative aromatization of 1,4-dihydropyridines and related substrates using gold nanoparticles supported on carbon nanotubes." Catalysis Science & Technology 6(17): 6476-6479.

 

Gravel, E ., I.N.N. Namboothiri and E. Doris (2016).   " Supramolecular assembly of gold nanoparticles on carbon nanotubes and catalysis of selected organic transformations. "   Synlett,   27 : 1179-1186.

 

Basu, P. , N. Shah, P. Prakash, S. Donck, E. Gravel, I.N.N. Namboothiri and E. Doris   (2016).   " Supramolecular assembly of gold nanoparticles on carbon nanotubes: Application to the mild catalytic oxidation of hydroxylamines. "   Nanomaterials   6 : 37.

 

Basu,   P., P. Prakash,   E. Gravel, N. Shah,   K. Bera,   E. Doris and I.N.N. Namboothiri   (2016).   " Carbon nanotube-ruthenium hybrids for the partial reduction of 2-nitrochalcones: an easy access to quinoline N -oxides. "   ChemCatChem   8 : 1298-1302.

 

Huan, T.N., P. Prakash, P. Simon, G. Rousse,   X. Xiangzhen,  V. Artero, E. Gravel, E. Doris and M. Fontecave   (2016).     " CO 2 reduction to CO in water: carbon nanotube-gold nanohybrid as selective and efficient electrocatalyst. "   ChemSusChem 9 :   2317-2320.

 

Partner 13

Bosc, D., E. Mouray, S. Cojean, C. H. Franco, P. M. Loiseau, L. H. Freitas-Junior, C. B. Moraes, P. Grellier and J. Dubois (2016). "Highly improved antiparasitic activity after introduction of an N-benzylimidazole moiety on protein farnesyltransferase inhibitors." European Journal of Medicinal Chemistry 109: 173-186.

 

Kenney IM, Beckstein O, Iorga BI. 2016. Prediction of cyclohexane-water distribution coefficients for the SAMPL5 data set using molecular dynamics simulations with the OPLS-AA force field. J. Comput. Aided Mol. Des. 30:1045-1058.

 

Martiny, V. Y., F. Martz, E. Selwa and B. I. Iorga (2016). "Blind Pose Prediction, Scoring, and Affinity Ranking of the CSAR 2014 Dataset." Journal of Chemical Information and Modeling 56(6): 996-1003.

 

Selwa, E., V. Y. Martiny and B. I. Iorga (2016). "Molecular docking performance evaluated on the D3R Grand Challenge 2015 drug-like ligand datasets." Journal of Computer-Aided Molecular Design 30(9): 829-839.

 

Partner 14

Arien, K. K., F. Baleux, D. Desjardins, F. Porrot, Y. M. Coic, J. Michiels, K. Bouchemal, D. Bonnaffe, T. Bruel, O. Schwartz, R. Le Grand, G. Vanham, N. Dereuddre-Bosquet and H. Lortat-Jacob (2016). "CD4-mimetic sulfopeptide conjugates display sub-nanomolar anti-HIV-1 activity and protect macaques against a SHIV162P3 vaginal challenge." Scientific Reports 6: 13.

 

Partner 15

Beniddir, M. A., L. Evanno, D. Joseph, A. Skiredj and E. Poupon (2016). "Emergence of diversity and stereochemical outcomes in the biosynthetic pathways of cyclobutane-centered marine alkaloid dimers." Natural Product Reports 33(7): 820-842.

 

Bony, N. F., D. Libong, P. Champy, A. K. Malan and P. Chaminade (2016). "Établissement du profil chromatographique liquide non aqueux des métabolites phytochimiques apolaires des phytomédicaments." Comptes Rendus Chimie 19(7): 863-875.

 

Chabrier, A., A. Bruneau, S. Benmahdjoub, B. Benmerad, S. Belaid, J.-D. Brion, M. Alami and S. Messaoudi (2016). "Stereoretentive Copper-Catalyzed Directed Thioglycosylation of C(sp2)−H Bonds of Benzamides." Chemistry – A European Journal 22(42): 15006-15010.

 

Daligaux, P., G. Bernadat, L. Tran, C. Cave, P. M. Loiseau, S. Pomel and H. D. Tap (2016). "Comparative study of structural models of Leishmania donovani and human GDP-mannose pyrophosphorylases." European Journal of Medicinal Chemistry 107: 109-118.

 

Kaffy, J., D. Brinet, J. L. Soulier, I. Correia, N. Tonali, K. F. Fera, Y. Iacone, A. R. F. Hoffmann, L. Khemtemourian, B. Crousse, M. Taylor, D. Allsop, M. Taverna, O. Lequin and S. Ongeri (2016). "Designed Glycopeptidomimetics Disrupt Protein-Protein Interactions Mediating Amyloid beta-Peptide Aggregation and Restore Neuroblastoma Cell Viability." Journal of Medicinal Chemistry 59(5): 2025-2040.

 

Lawson, M., J. Rodrigo, B. Baratte, T. Robert, C. Delehouze, O. Lozach, S. Ruchaud, S. Bach, J. D. Brion, M. Alami and A. Hamze (2016). "Synthesis, biological evaluation and molecular modeling studies of imidazo 1,2-alpha pyridines derivatives as protein kinase inhibitors." European Journal of Medicinal Chemistry 123: 105-114.

 

Le Douaron, G., L. Ferrie, J. E. Sepulveda-Diaz, M. Amar, A. Harfouche, B. Seon-Meniel, R. Raisman-Vozari, P. P. Michel and B. Figadere (2016). "New 6-Aminoquinoxaline Derivatives with Neuroprotective Effect on Dopaminergic Neurons in Cellular and Animal Parkinson Disease Models." Journal of Medicinal Chemistry 59(13): 6169-6186.

 

Luong, T. T. H., J. D. Brion, E. Lescop, M. Alami and S. Messaoudi (2016). "Intramolecular Pd-Catalyzed Arylation of 1-Amidosugars: A New Route to N-Glycosyl Quinolin-2-ones." Organic Letters 18(9): 2126-2129.

 

Naret, T., P. Retailleau, J. Bignon, J. D. Brion, M. Alami and A. Hamze (2016). "Palladium-Catalyzed One-Pot Synthesis of 5-(1-Arylvinyl)-1H-benzimidazoles: Overcoming the Limitation of Acetamide Partners." Advanced Synthesis & Catalysis 358(11): 1833-1847.

 

Reddy, K. H. V., J. D. Brion, S. Messaoudi and M. Alami (2016). "Synthesis of Biheterocycles Based on Quinolinone, Chromone, and Coumarin Scaffolds by Palladium-Catalyzed Decarboxylative Couplings." Journal of Organic Chemistry 81(2): 424-432.

 

Roel, M., J. A. Rubiolo, J. Guerra-Varela, S. B. L. Silva, O. P. Thomas, P. Cabezas-Sainz, L. Sánchez, R. López and L. M. Botana (2016). "Marine guanidine alkaloids crambescidins inhibit tumor growth and activate intrinsic apoptotic signaling inducing tumor regression in a colorectal carcinoma zebrafish xenograft model." Oncotarget 7(50).

 

Skiredj, A., M. A. Beniddir, L. Evanno and E. Poupon (2016). "Mimicking the Main Events of the Biosynthesis of Drimentines: Synthesis of Delta(8 ')-Isodrimentine A and Related Compounds." European Journal of Organic Chemistry(17): 2954-2958.

 

Vardhan Reddy, K. H., J.-D. Brion, S. Messaoudi and M. Alami (2016). "Synthesis of Biheterocycles Based on Quinolinone, Chromone, and Coumarin Scaffolds by Palladium-Catalyzed Decarboxylative Couplings." The Journal of Organic Chemistry 81(2): 424-432.

 

Zhao, G. K., L. Z. Yuan, M. Roudier, J. F. Peyrat, A. Hamze, J. D. Brion, O. Provot and M. Alami (2016). "A Convenient Metal- Free Synthesis of (E)-3-Styrylisocoumarins through Annulation of (E)-1,4-Diarylenynes." Synthesis-Stuttgart 48(19): 3382-3392.

 

Atto Al-Shuaeeb, R. A.; Kolodych, S.; Koniev, O.; Delacroix, S.; Erb, S.; Nicolaÿ, S.; Cintrat, J.-C.; Brion, J.-D.; Cianférani, S.; Alami, M.; Wagner, A.; Messaoudi, S. Palladium catalyzed chemoselective and biocompatible functionalization of cysteine-containing molecules at Room Temperature. Chem. Eur. J. 2016, 22, 11365

 

Sauvage, F.; Franzé S.; Bruneau, A.; Alami, M.; Denis S.; Nicolas, V.; Lesieur, S.; Legrand, F.-X.; Baratt, G.; Messaoudi, S.; Vergnaud-Gauduchon, J. Formulation and in vitro efficacy of liposomes containing the hsp90 inhibitor 6BrCaQ in prostate cancer cells. Int. J. Pharmaceut. 2016, 499, 101-109.

 

 

Partner 16

Aragao-Santiago, L., H. Hillaireau, N. Grabowski, S. Mura, T. L. Nascimento, S. Dufort, J.-L. Coll, N. Tsapis and E. Fattal (2016). "Compared in vivo toxicity in mice of lung delivered biodegradable and non-biodegradable nanoparticles." Nanotoxicology 10(3): 292-302.

 

Bédouet, L., L. Moine, E. Servais, A. Beilvert, D. Labarre and A. Laurent (2016). "Tunable delivery of niflumic acid from resorbable embolization microspheres for uterine fibroid embolization." International Journal of Pharmaceutics 511(1): 253-261.

 

Boissenot, T., A. Bordat, E. Fattal and N. Tsapis (2016). "Ultrasound-triggered drug delivery for cancer treatment using drug delivery systems: From theoretical considerations to practical applications." Journal of Controlled Release 241: 144-163.

 

Diou, O., A. Brulet, G. Pehau-Arnaudet, E. Morvan, R. Berti, K. Astafyeva, N. Taulier, E. Fattal and N. Tsapis (2016). "PEGylated nanocapsules of perfluorooctyl bromide: Mechanism of formation, influence of polymer concentration on morphology and mechanical properties." Colloids and Surfaces B-Biointerfaces 146: 762-769.

 

El Hadri, M., A. Achahbar, J. El Khamkhami, B. Khelifa, V. Faivre, O. Abbas and S. Bresson (2016). "Lyotropic behavior of Gelucire 50/13 by XRD, Raman and IR spectroscopies according to hydration." Chemistry and Physics of Lipids 200: 11-23.

 

Lintingre, E., F. Lequeux, L. Talini and N. Tsapis (2016). "Control of particle morphology in the spray drying of colloidal suspensions." Soft Matter 12(36): 7435-7444.

 

Ruge, C. A., A. Bohr, M. Beck-Broichsitter, V. Nicolas, N. Tsapis and E. Fattal (2016). "Disintegration of nano-embedded microparticles after deposition on mucus: A mechanistic study." Colloids and Surfaces B-Biointerfaces 139: 219-227.

 

Sarrazin, B., N. Tsapis, L. Mousnier, N. Taulier, W. Urbach and P. Guenoun (2016). "AFM Investigation of Liquid-Filled Polymer Microcapsules Elasticity." Langmuir 32(18): 4610-4618.

 

Secrétan, P.-H., M. Karoui, M. Bernard, N. Ghermani, F. Safta, N. Yagoubi and B. Do (2016). "Photodegradation of aqueous argatroban investigated by LC/MSn: Photoproducts, transformation processes and potential implications." Journal of Pharmaceutical and Biomedical Analysis 131: 223-232.

 

Zerkoune, L., S. Lesieur, J.-L. Putaux, L. Choisnard, A. Geze, D. Wouessidjewe, B. Angelov, C. Vebert-Nardin, J. Doutch and A. Angelova (2016). "Mesoporous self-assembled nanoparticles of biotransesterifiecyclodextrins and nonlamellar lipids as carriers of water-insoluble substances." Soft Matter 12(36): 7539-7550.

 

Partner 3 et 4

 

Vincent, F. B., S. Pavy, R. Krzysiek, T. Lequerre, J. Sellam, Y. Taoufik, X. Mariette and C. Miceli-Richard (2016). "Effect of serum anti-tumour necrosis factor (TNF) drug trough concentrations and antidrug antibodies (ADAb) to further anti-TNF short-term effectiveness after switching in rheumatoid arthritis and axial spondyloarthritis." Joint Bone Spine 83(5): 595-597.

 

Partner 7 et 13


Naas, T., L. Dortet and B. I. Iorga (2016). "Structural and Functional Aspects of Class A Carbapenemases." Current Drug Targets 17(9): 1006-1028.

 

Partner 11 et 12

Barbier, J., J. C. Cintrat and D. Gillet (2016). "Intracellular pathogens convert macrophages from death traps into hospitable homes." Febs Journal 283(4): 595-597.

 

 

Harrison, K., I. R. Haga, T. Pechenick Jowers, S. Jasim, J.-C. Cintrat, D. Gillet, T. Schmitt-John, P. Digard and P. M. Beard (2016). "Vaccinia Virus Uses Retromer-Independent Cellular Retrograde Transport Pathways To Facilitate the Wrapping of Intracellular Mature Virions during Virus Morphogenesis." Journal of Virology 90(22): 10120-10132.

 

 

Yang, B., X. Ming, H. Abdelkafi, V. Pons, A. Michau, D. Gillet, J.-C. Cintrat, J. Barbier and R. Juliano (2016). "Retro-1 Analogues Differentially Affect Oligonucleotide Delivery and Toxin Trafficking." ChemMedChem 11(22): 2506-2510.

 

 

Herweg, J. A., V. Pons, D. Becher, M. Hecker, G. Krohne, J. Barbier, H. Berger, T. Rudel and A. Mehlitz (2016). "Proteomic analysis of the Simkania-containing vacuole: the central role of retrograde transport." Mol Microbiol 99(1): 151-171.

 

Partner 11 et 13

 

Couesnon, A., R. Aráoz, B. Iorga, E. Benoit, M. Reynaud, D. Servent and J. Molgó (2016). "The Dinoflagellate Toxin 20-Methyl Spirolide-G Potently Blocks Skeletal Muscle and Neuronal Nicotinic Acetylcholine Receptors." Toxins 8(9): 249.

 

Partner 12 et 15

Al-Shuaeeb, R. A. A., S. Kolodych, O. Koniev, S. Delacroix, S. Erb, S. Nicolay, J. C. Cintrat, J. D. Brion, S. Cianferani, M. Alami, A. Wagner and S. Messaoudi (2016). "Palladium-Catalyzed Chemoselective and Biocompatible Functionalization of Cysteine-Containing Molecules at Room Temperature." Chemistry-a European Journal 22(32): 11365-11370.

 

Partner 13 et 15

 

Kousara, M., F. Le Bideau, R. Ibrahim, A. Ferry, P. E. Venot, C. Dejean, J. Raingeaud, J. Dubois, P. Retailleau and F. Dumas (2016). "Suberosanes as Potential Antitumor Agents: First Enantioselective Total Synthesis of (1S)-Suberosanone and Configurational Assignment of Suberosenol A." Synthesis-Stuttgart 48(11): 1637-1646.

Partner 15 et 16

 

Sauvage, F., S. Franze, A. Bruneau, M. Alami, S. Denis, V. Nicolas, S. Lesieur, F. X. Legrand, G. Barratt, S. Messaoudi and J. Vergnaud-Gauduchon (2016). "Formulation and in vitro efficacy of liposomes containing the Hsp90 inhibitor 6BrCaQ in prostate cancer cells." International Journal of Pharmaceutics 499(1-2): 101-109.

 

 

Suyyagh-Albouz, S., R. Al-Rifai, Z. Song, L. Wild, V. L. Le Moal, V. Nicolas, F. Bruxel, P. Loiseau, H. Teixeira, B. Meunier, N. Tsapis, E. Fattal and S. Cojean (2016). "Atovaquone encapsulation into nanoemulsions for better efficacy on mitochondria of resistant Plasmodium falciparum strain." European Journal of Clinical Investigation 46: 67-67.